Immunotoxicological Evaluation of Genetically Modified Rice Expressing Cry1Ab/Ac Protein (TT51-1) by a 6-Month Feeding Study on Cynomolgus Monkeys

Xiaoyan Tan; Xiaobing Zhou; Yao Tang; Jianjun Lv; Lin Zhang; Li Sun; Yanwei Yang; Yufa Miao; Hua Jiang; Gaofeng Chen; Zhiying Huang; Xue Wang

doi:10.1371/journal.pone.0163879

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Open Access

Peer-reviewed

Research Article

Immunotoxicological Evaluation of Genetically Modified Rice Expressing Cry1Ab/Ac Protein (TT51-1) by a 6-Month Feeding Study on Cynomolgus Monkeys

Xiaoyan Tan,

Affiliations Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China, Center of Safety Evaluation on New Drug, School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, Guangdong Province, People’s Republic of China
⨯
Xiaobing Zhou,

Affiliation Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
⨯
Yao Tang,

Affiliation Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
⨯
Jianjun Lv,

Affiliation Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
⨯
Lin Zhang,

Affiliation Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
⨯
Li Sun,

Affiliation Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
⨯
Yanwei Yang,

Affiliation Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
⨯
Yufa Miao,

Affiliation Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
⨯
Hua Jiang,

Affiliation Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China
⨯
Gaofeng Chen,

Affiliations Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China, Center of Safety Evaluation on New Drug, School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, Guangdong Province, People’s Republic of China
⨯
Zhiying Huang ,

* E-mail: xue_wang@nifdc.org.cn (XW); hzhiying@mail.sysu.edu.cn (ZYH)

Affiliation Center of Safety Evaluation on New Drug, School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, Guangdong Province, People’s Republic of China
⨯
Xue Wang

* E-mail: xue_wang@nifdc.org.cn (XW); hzhiying@mail.sysu.edu.cn (ZYH)

Affiliations Key Laboratory of Beijing for Safety Evaluation of Drugs, National Center for Safety Evaluation of Drugs, National Institutes for Food and Drug Control, Beijing, People’s Republic of China, Center of Safety Evaluation on New Drug, School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, Guangdong Province, People’s Republic of China
⨯

Immunotoxicological Evaluation of Genetically Modified Rice Expressing Cry1Ab/Ac Protein (TT51-1) by a 6-Month Feeding Study on Cynomolgus Monkeys

Xiaoyan Tan,
Xiaobing Zhou,
Yao Tang,
Jianjun Lv,
Lin Zhang,
Li Sun,
Yanwei Yang,
Yufa Miao,
Hua Jiang,
Gaofeng Chen

Published: September 29, 2016
https://doi.org/10.1371/journal.pone.0163879

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