Down-Regulation of CXCL12/CXCR4 Expression Alleviates Ischemia-Reperfusion-Induced Inflammatory Pain via Inhibiting Glial TLR4 Activation in the Spinal Cord

Open Access

Peer-reviewed

Research Article

Down-Regulation of CXCL12/CXCR4 Expression Alleviates Ischemia-Reperfusion-Induced Inflammatory Pain via Inhibiting Glial TLR₄ Activation in the Spinal Cord

Xiao-Qian Li,

Affiliation Department of Anesthesiology, First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning, China
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Zai-Li Zhang,

Affiliation Department of Anesthesiology, First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning, China
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Wen-Fei Tan,

Affiliation Department of Anesthesiology, First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning, China
⨯
Xi-Jia Sun,

Affiliation Department of Anesthesiology, First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning, China
⨯
Hong Ma

* E-mail: mahong5466@yahoo.com

Affiliation Department of Anesthesiology, First Affiliated Hospital, China Medical University, Shenyang 110001, Liaoning, China
⨯

Pain
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Inflammation
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Spinal cord
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Toll-like receptors
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Microglial cells
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Astrocytes
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Chemokines
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Cytokines
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