Arachidonic Acid Metabolite 19(S)-HETE Induces Vasorelaxation and Platelet Inhibition by Activating Prostacyclin (IP) Receptor

Open Access

Peer-reviewed

Research Article

Sorin Tunaru ,

* E-mail: sorin.tunaru@mpi-bn.mpg.de (ST); stefan.offermanns@mpi-bn.mpg.de (SO)

Affiliation Max-Planck-Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231 Bad Nauheim, Germany
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Ramesh Chennupati,

Affiliation Max-Planck-Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231 Bad Nauheim, Germany
⨯
Rolf M. Nüsing,

Affiliation Institute for Clinical Pharmacology, J.W. Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany
⨯
Stefan Offermanns

* E-mail: sorin.tunaru@mpi-bn.mpg.de (ST); stefan.offermanns@mpi-bn.mpg.de (SO)

Affiliations Max-Planck-Institute for Heart and Lung Research, Department of Pharmacology, Ludwigstr. 43, 61231 Bad Nauheim, Germany, Medical Faculty, J.W. Goethe University Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany
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Intracellular receptors
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Platelet aggregation
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Platelets
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Small interfering RNA
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Transfection
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G protein coupled receptors
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Prostacyclin
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Cell binding assay
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