Oxazin-5-Ones as a Novel Class of Penicillin Binding Protein Inhibitors: Design, Synthesis and Structure Activity Relationship

Open Access

Peer-reviewed

Research Article

Efeturi Abraham Onoabedje ,

* E-mail: efeturi.onoabedje@unn.edu.ng (EAO); akachukwu.ibezim@unn.edu.ng (AI)

Affiliation Department of Pure & Industrial Chemistry, University of Nigeria, Nsukka, Enugu State, Nigeria
⨯
Akachukwu Ibezim ,

* E-mail: efeturi.onoabedje@unn.edu.ng (EAO); akachukwu.ibezim@unn.edu.ng (AI)

Affiliation Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria
⨯
Sunday Nwankwor Okafor,

Affiliation Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria
⨯
Ufuoma Shalom Onoabedje,

Affiliation Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria
⨯
Uchechukwu Chris Okoro

Affiliation Department of Pure & Industrial Chemistry, University of Nigeria, Nsukka, Enugu State, Nigeria
⨯

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Chemical synthesis
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Ethers
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Antibiotics
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Column chromatography
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Drug interactions
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Drug screening
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Drug discovery
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Penicillin
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