Specific Endocytosis Blockade of Trypanosoma cruzi Exposed to a Poly-LAcNAc Binding Lectin Suggests that Lectin-Sugar Interactions Participate to Receptor-Mediated Endocytosis

Sébastien Brosson; Frédéric Fontaine; Marjorie Vermeersch; David Perez-Morga; Etienne Pays; Sabrina Bousbata; Didier Salmon

doi:10.1371/journal.pone.0163302

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Specific Endocytosis Blockade of Trypanosoma cruzi Exposed to a Poly-LAcNAc Binding Lectin Suggests that Lectin-Sugar Interactions Participate to Receptor-Mediated Endocytosis

Sébastien Brosson,

Affiliation Laboratory of Molecular Parasitology, Institute of Molecular Biology and Medicine, Université Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, B-6041 Gosselies, Belgium
⨯
Frédéric Fontaine,

Affiliation Laboratory of Molecular Parasitology, Institute of Molecular Biology and Medicine, Université Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, B-6041 Gosselies, Belgium
⨯
Marjorie Vermeersch,

Affiliation Center for Microscopy and Molecular Imaging-CMMI, Université Libre de Bruxelles, 8 rue Adrienne Bolland, B-6041 Gosselies, Belgium
⨯
David Perez-Morga,

Affiliations Laboratory of Molecular Parasitology, Institute of Molecular Biology and Medicine, Université Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, B-6041 Gosselies, Belgium, Center for Microscopy and Molecular Imaging-CMMI, Université Libre de Bruxelles, 8 rue Adrienne Bolland, B-6041 Gosselies, Belgium
⨯
Etienne Pays,

Affiliation Laboratory of Molecular Parasitology, Institute of Molecular Biology and Medicine, Université Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, B-6041 Gosselies, Belgium
⨯
Sabrina Bousbata ,

* E-mail: salmon@bioqmed.ufrj.br (DS); sabrina.bousbata@ulb.ac.be (SB)

Affiliation Laboratory of Molecular Parasitology, Institute of Molecular Biology and Medicine, Université Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, B-6041 Gosselies, Belgium
⨯
Didier Salmon

* E-mail: salmon@bioqmed.ufrj.br (DS); sabrina.bousbata@ulb.ac.be (SB)

Affiliations Laboratory of Molecular Parasitology, Institute of Molecular Biology and Medicine, Université Libre de Bruxelles, 12 rue des Professeurs Jeener et Brachet, B-6041 Gosselies, Belgium, Institute of Medical Biochemistry Leopoldo de Meis, Centro de Ciências e da Saúde, Federal University of Rio de Janeiro, Av. Brigadeiro Trompowsky, Rio de Janeiro, 21941-590, Brazil
⨯

Specific Endocytosis Blockade of Trypanosoma cruzi Exposed to a Poly-LAcNAc Binding Lectin Suggests that Lectin-Sugar Interactions Participate to Receptor-Mediated Endocytosis

Sébastien Brosson,
Frédéric Fontaine,
Marjorie Vermeersch,
David Perez-Morga,
Etienne Pays,
Sabrina Bousbata,
Didier Salmon

Published: September 29, 2016
https://doi.org/10.1371/journal.pone.0163302

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Trypanosoma cruzi
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Trypanosoma
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Glycoproteins
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Trypanosoma brucei gambiense
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