The gp63 Gene Cluster Is Highly Polymorphic in Natural Leishmania (Viannia) braziliensis Populations, but Functional Sites Are Conserved

Lilian S. Medina; Bruno Araújo Souza; Adriano Queiroz; Luiz Henrique Guimarães; Paulo Roberto Lima Machado; Edgar M Carvalho; Mary Edythe Wilson; Albert Schriefer

doi:10.1371/journal.pone.0163284

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Peer-reviewed

Research Article

The gp63 Gene Cluster Is Highly Polymorphic in Natural Leishmania (Viannia) braziliensis Populations, but Functional Sites Are Conserved

Lilian S. Medina,

Affiliation Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil
⨯
Bruno Araújo Souza,

Affiliation Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil
⨯
Adriano Queiroz,

Affiliation Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil
⨯
Luiz Henrique Guimarães,

Affiliations Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil, Instituto Nacional de Ciência e Tecnologia – Doenças Tropicais (INCT-DT), Brazil
⨯
Paulo Roberto Lima Machado,

Affiliations Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil, Instituto Nacional de Ciência e Tecnologia – Doenças Tropicais (INCT-DT), Brazil
⨯
Edgar M Carvalho,

Affiliations Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil, Instituto Nacional de Ciência e Tecnologia – Doenças Tropicais (INCT-DT), Brazil, Centro de Pesquisa Gonçalo Moniz (Fiocruz), Salvador, Bahia, Brazil
⨯
Mary Edythe Wilson,

Affiliation Departments of Internal Medicine and Microbiology, University of Iowa and the VA Medical Center, Iowa City, Iowa, United States of America
⨯
Albert Schriefer

* E-mail: aschriefer@ufba.br

Affiliations Serviço de Imunologia, Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil, Instituto Nacional de Ciência e Tecnologia – Doenças Tropicais (INCT-DT), Brazil, Departamento de Ciências da Biointeração, Instituto de Ciências da Saúde, Universidade Federal da Bahia, Salvador, Bahia, Brazil
⨯

The gp63 Gene Cluster Is Highly Polymorphic in Natural Leishmania (Viannia) braziliensis Populations, but Functional Sites Are Conserved

Lilian S. Medina,
Bruno Araújo Souza,
Adriano Queiroz,
Luiz Henrique Guimarães,
Paulo Roberto Lima Machado,
Edgar M Carvalho,
Mary Edythe Wilson,
Albert Schriefer

Published: September 20, 2016
https://doi.org/10.1371/journal.pone.0163284

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Sequence alignment
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