Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD

• Martin A. Bewley ,

  * E-mail: bewleyma@gmail.com

  Affiliation Department of Infection, Immunity and Cardiovascular Disease and The Florey Institute for Host-Pathogen Interactions, University of Sheffield Medical School, Sheffield, United Kingdom

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• Kylie B. R. Belchamber,

  Affiliation Airway Disease National Heart and Lung Institute, Imperial College London, London, United Kingdom

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• Kirandeep K. Chana,

  Affiliation Airway Disease National Heart and Lung Institute, Imperial College London, London, United Kingdom

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• Richard C. Budd,

  Affiliations Department of Infection, Immunity and Cardiovascular Disease and The Florey Institute for Host-Pathogen Interactions, University of Sheffield Medical School, Sheffield, United Kingdom, Sheffield Teaching Hospitals Foundation Trust, Sheffield, United Kingdom, Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom

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• Gavin Donaldson,

  Affiliation Airway Disease National Heart and Lung Institute, Imperial College London, London, United Kingdom

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• Jadwiga A. Wedzicha,

  Affiliation Airway Disease National Heart and Lung Institute, Imperial College London, London, United Kingdom

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• Christopher E. Brightling,

  Affiliation Institute for Lung Heath, University of Leicester, Leicester, United Kingdom

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• Iain Kilty,

  Affiliation Pfizer Inc, Cambridge, Massachusetts, United States of America

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• Louise E. Donnelly,

  Affiliation Airway Disease National Heart and Lung Institute, Imperial College London, London, United Kingdom

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• Peter J. Barnes,

  Affiliation Airway Disease National Heart and Lung Institute, Imperial College London, London, United Kingdom

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• Dave Singh,

  Affiliation Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester NHS Foundation Trust, Manchester, United Kingdom

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• Moira K. B. Whyte ,

  ¶‡ MKBW and DHD acted as joint senior authors.

  Affiliation Department of Respiratory Medicine and MRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom

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• David H. Dockrell ,

  ¶‡ MKBW and DHD acted as joint senior authors.

  Affiliations Department of Infection, Immunity and Cardiovascular Disease and The Florey Institute for Host-Pathogen Interactions, University of Sheffield Medical School, Sheffield, United Kingdom, Sheffield Teaching Hospitals Foundation Trust, Sheffield, United Kingdom

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• COPDMAP

  ¶A list of COPDMAP consortium members is provided online at COPDMAP.com. The complete membership of the author group can be found in the Acknowledgments.

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