Exploring the Inflammatory Metabolomic Profile to Predict Response to TNF-α Inhibitors in Rheumatoid Arthritis

• Bart V. J. Cuppen ,

  Contributed equally to this work with: Bart V. J. Cuppen, Junzeng Fu

  Affiliation Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands

  ⨯
• Junzeng Fu ,

  Contributed equally to this work with: Bart V. J. Cuppen, Junzeng Fu

  * E-mail: j.fu@lacdr.leidenuniv.nl

  Affiliations Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands, Sino-Dutch center for Preventive and Personalized Medicine, Zeist, The Netherlands

  ⨯
• Herman A. van Wietmarschen,

  Affiliations Sino-Dutch center for Preventive and Personalized Medicine, Zeist, The Netherlands, TNO, Netherlands Organization for Applied Scientific Research, Microbiology & Systems Biology, Zeist, The Netherlands

  ⨯
• Amy C. Harms,

  Affiliations Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands, Netherlands Metabolomics Center, Leiden, The Netherlands

  ⨯
• Slavik Koval,

  Affiliations Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands, Netherlands Metabolomics Center, Leiden, The Netherlands

  ⨯
• Anne C. A. Marijnissen,

  Affiliation Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands

  ⨯
• Judith J. W. Peeters,

  Affiliation St Jansdal hospital, Harderwijk, The Netherlands

  ⨯
• Johannes W. J. Bijlsma,

  Affiliation Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands

  ⨯
• Janneke Tekstra,

  Affiliation Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands

  ⨯
• Jacob M. van Laar,

  Affiliation Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands

  ⨯
• Thomas Hankemeier,

  Affiliations Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands, Netherlands Metabolomics Center, Leiden, The Netherlands

  ⨯
• Floris P. J. G. Lafeber,

  Affiliation Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands

  ⨯
• Jan van der Greef,

  Affiliations Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands, Sino-Dutch center for Preventive and Personalized Medicine, Zeist, The Netherlands, TNO, Netherlands Organization for Applied Scientific Research, Microbiology & Systems Biology, Zeist, The Netherlands, Netherlands Metabolomics Center, Leiden, The Netherlands

  ⨯
• on behalf of all Society for Rheumatology Research Utrecht investigators

  ¶Membership of the Society for Rheumatology Research Utrecht (SRU) investigators is provided in the Acknowledgments.

  ⨯