Thioredoxin Inhibitors Attenuate Platelet Function and Thrombus Formation

Open Access

Peer-reviewed

Research Article

Clive Metcalfe,

Affiliation Oxford Molecular and Pathology Institute, South Parks Road, Oxford, OX1 3RE, United Kingdom
⨯
Anjana Ramasubramoni,

Affiliation Oxford Molecular and Pathology Institute, South Parks Road, Oxford, OX1 3RE, United Kingdom
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Giordano Pula,

Affiliation Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom
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Matthew T. Harper,

Affiliation Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, United Kingdom
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Stuart J. Mundell ,

* E-mail: s.j.mundell@bristol.ac.uk

Affiliation Department of Physiology, Pharmacology and Neuroscience, Medical Sciences Building, University of Bristol, University Walk, Bristol, BS8 1TD, United Kingdom
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Carmen H. Coxon

Affiliation Department of Physiology, Pharmacology and Neuroscience, Medical Sciences Building, University of Bristol, University Walk, Bristol, BS8 1TD, United Kingdom
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Platelets
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Platelet activation
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Thiols
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Platelet aggregation
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Blood flow
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Integrins
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Collagens
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Reactive oxygen species
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