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Open Access
Peer-reviewed
Research Article
Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome
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Nick M. Powell ,
* E-mail: nicholas.powell.11@ucl.ac.uk
Affiliations Translational Imaging Group, Centre for Medical Image Computing, University College London, 3rd Floor, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom, Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, Paul O’Gorman Building, 72 Huntley Street, London WC1E 6DD, United Kingdom
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Marc Modat,
Affiliation Translational Imaging Group, Centre for Medical Image Computing, University College London, 3rd Floor, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom
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M. Jorge Cardoso,
Affiliation Translational Imaging Group, Centre for Medical Image Computing, University College London, 3rd Floor, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom
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Da Ma,
Affiliations Translational Imaging Group, Centre for Medical Image Computing, University College London, 3rd Floor, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom, Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, Paul O’Gorman Building, 72 Huntley Street, London WC1E 6DD, United Kingdom
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Holly E. Holmes,
Affiliation Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, Paul O’Gorman Building, 72 Huntley Street, London WC1E 6DD, United Kingdom
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Yichao Yu,
Affiliation Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, Paul O’Gorman Building, 72 Huntley Street, London WC1E 6DD, United Kingdom
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James O’Callaghan,
Affiliation Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, Paul O’Gorman Building, 72 Huntley Street, London WC1E 6DD, United Kingdom
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Jon O. Cleary,
Affiliations Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, Paul O’Gorman Building, 72 Huntley Street, London WC1E 6DD, United Kingdom, Melbourne Brain Centre Imaging Unit, Department of Anatomy and Neuroscience, University of Melbourne, Parkville, Victoria 3052, Australia
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Ben Sinclair,
Affiliation Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, Paul O’Gorman Building, 72 Huntley Street, London WC1E 6DD, United Kingdom
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Frances K. Wiseman,
Affiliation Department of Neurodegenerative Disease, Institute of Neurology, University College, London WC1N 3BG, United Kingdom
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Victor L. J. Tybulewicz,
Affiliations The Francis Crick Institute, Mill Hill Laboratory, London NW7 1AA, United Kingdom, Imperial College, London W12 0NN, United Kingdom
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Elizabeth M. C. Fisher,
Affiliation Department of Neurodegenerative Disease, Institute of Neurology, University College, London WC1N 3BG, United Kingdom
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Mark F. Lythgoe,
Affiliation Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, Paul O’Gorman Building, 72 Huntley Street, London WC1E 6DD, United Kingdom
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Sébastien Ourselin
Affiliation Translational Imaging Group, Centre for Medical Image Computing, University College London, 3rd Floor, Wolfson House, 4 Stephenson Way, London NW1 2HE, United Kingdom
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Fully-Automated μMRI Morphometric Phenotyping of the Tc1 Mouse Model of Down Syndrome
- Nick M. Powell,
- Marc Modat,
- M. Jorge Cardoso,
- Da Ma,
- Holly E. Holmes,
- Yichao Yu,
- James O’Callaghan,
- Jon O. Cleary,
- Ben Sinclair,
- Frances K. Wiseman
- Published: September 22, 2016
- https://doi.org/10.1371/journal.pone.0162974