Development and Evaluation of a Novel Mucoadhesive Film Containing Acmella oleracea Extract for Oral Mucosa Topical Anesthesia

• Verônica Santana de Freitas-Blanco,

  Affiliations Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil, Chemical, Biological and Agricultural Research Center (CPQBA), University of Campinas, Paulinia, Brazil

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• Michelle Franz-Montan,

  Affiliation Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil

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• Francisco Carlos Groppo,

  Affiliation Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil

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• João Ernesto de Carvalho,

  Affiliations Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil, Chemical, Biological and Agricultural Research Center (CPQBA), University of Campinas, Paulinia, Brazil, Faculty of Pharmaceutical Sciences, University of Campinas, Campinas, Brazil

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• Glyn Mara Figueira,

  Affiliation Chemical, Biological and Agricultural Research Center (CPQBA), University of Campinas, Paulinia, Brazil

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• Luciano Serpe,

  Affiliation Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil

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• Ilza Maria Oliveira Sousa,

  Affiliation Chemical, Biological and Agricultural Research Center (CPQBA), University of Campinas, Paulinia, Brazil

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• Viviane Aparecida Guilherme Damasio,

  Affiliation Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, Brazil

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• Lais Thiemi Yamane,

  Affiliation Chemical, Biological and Agricultural Research Center (CPQBA), University of Campinas, Paulinia, Brazil

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• Eneida de Paula,

  Affiliation Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, Brazil

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• Rodney Alexandre Ferreira Rodrigues

  * E-mail: rodney@cpqba.unicamp.br

  Affiliations Department of Physiological Sciences, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil, Chemical, Biological and Agricultural Research Center (CPQBA), University of Campinas, Paulinia, Brazil

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