Activation of Peroxisome Proliferator-Activated Receptor Alpha Improves Aged and UV-Irradiated Skin by Catalase Induction

Mi Hee Shin; Se-Rah Lee; Min-Kyoung Kim; Chang-Yup Shin; Dong Hun Lee; Jin Ho Chung

doi:10.1371/journal.pone.0162628

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Peer-reviewed

Research Article

Activation of Peroxisome Proliferator-Activated Receptor Alpha Improves Aged and UV-Irradiated Skin by Catalase Induction

Mi Hee Shin,

Affiliations Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea, Institute of Human-Environment Interface Biology, Medical Research Center, Seoul National University, Seoul, Republic of Korea
⨯
Se-Rah Lee,

Affiliations Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea, Institute of Human-Environment Interface Biology, Medical Research Center, Seoul National University, Seoul, Republic of Korea
⨯
Min-Kyoung Kim,

Affiliations Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea, Institute of Human-Environment Interface Biology, Medical Research Center, Seoul National University, Seoul, Republic of Korea
⨯
Chang-Yup Shin,

Affiliations Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea, Institute of Human-Environment Interface Biology, Medical Research Center, Seoul National University, Seoul, Republic of Korea
⨯
Dong Hun Lee ,

Contributed equally to this work with: Dong Hun Lee, Jin Ho Chung

* E-mail: jhchung@snu.ac.kr (JHC); ivymed27@snu.ac.kr (DHL)

Affiliations Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea, Institute of Human-Environment Interface Biology, Medical Research Center, Seoul National University, Seoul, Republic of Korea
⨯
Jin Ho Chung

Contributed equally to this work with: Dong Hun Lee, Jin Ho Chung

* E-mail: jhchung@snu.ac.kr (JHC); ivymed27@snu.ac.kr (DHL)

Affiliations Department of Dermatology, Seoul National University College of Medicine, Seoul, Republic of Korea, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea, Institute of Human-Environment Interface Biology, Medical Research Center, Seoul National University, Seoul, Republic of Korea, Institute on Aging, Seoul National University, Seoul, Republic of Korea
⨯

Activation of Peroxisome Proliferator-Activated Receptor Alpha Improves Aged and UV-Irradiated Skin by Catalase Induction

Mi Hee Shin,
Se-Rah Lee,
Min-Kyoung Kim,
Chang-Yup Shin,
Dong Hun Lee,
Jin Ho Chung

Published: September 9, 2016
https://doi.org/10.1371/journal.pone.0162628

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Catalases
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Fibroblasts
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Photodermatology and skin aging
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Skin
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Small interfering RNA
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Transfection
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Ultraviolet radiation
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Inflammation
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