High-Resolution Identification of Specificity Determining Positions in the LacI Protein Family Using Ensembles of Sub-Sampled Alignments

Open Access

Peer-reviewed

Research Article

Roman Sloutsky,

Affiliations Biomedical Engineering Department, Washington University in St. Louis, St. Louis, Missouri, 63130, United States of America, Center for Biological Systems Engineering, Washington University in St. Louis, St. Louis, Missouri, 63130, United States of America
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Kristen M. Naegle

* E-mail: knaegle@wustl.edu

Affiliations Biomedical Engineering Department, Washington University in St. Louis, St. Louis, Missouri, 63130, United States of America, Center for Biological Systems Engineering, Washington University in St. Louis, St. Louis, Missouri, 63130, United States of America

http://orcid.org/0000-0001-7146-9592

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Sequence alignment
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Multiple alignment calculation
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Allosteric regulation
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Protein structure comparison
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Protein sequencing
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Hydrogen bonding
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Protein structure
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Amino acid sequence analysis
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