A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration

• Hyun Seung Ban ,

  Contributed equally to this work with: Hyun Seung Ban, Xuezhen Xu

  Affiliations Metabolic Regulation Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea, Biomolecular Science, University of Science and Technology, Daejeon, Korea

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• Xuezhen Xu ,

  Contributed equally to this work with: Hyun Seung Ban, Xuezhen Xu

  Affiliation College of Pharmacy, Dongguk University-Seoul, Goyang, Korea

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• Kusik Jang,

  Affiliation College of Pharmacy, Dongguk University-Seoul, Goyang, Korea

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• Inhyub Kim,

  Affiliations Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea, Functional Genomics, University of Science and Technology, Daejeon, Korea

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• Bo-Kyung Kim,

  Affiliation Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea

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• Kyeong Lee ,

  * E-mail: misun@kribb.re.kr (MW); kaylee@donggkuk.edu (KL)

  Affiliation College of Pharmacy, Dongguk University-Seoul, Goyang, Korea

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• Misun Won

  * E-mail: misun@kribb.re.kr (MW); kaylee@donggkuk.edu (KL)

  Affiliations Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea, Functional Genomics, University of Science and Technology, Daejeon, Korea

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