Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes

Jianjia Fan; Shahab Zareyan; Wenchen Zhao; Yoko Shimizu; Tom A. Pfeifer; Jun-Hyung Tak; Murray B. Isman; Bernard Van den Hoven; Mark E. Duggan; Michael W. Wood; Cheryl L. Wellington; Iva Kulic

doi:10.1371/journal.pone.0162384

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Open Access

Peer-reviewed

Research Article

Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes

Jianjia Fan ,

Contributed equally to this work with: Jianjia Fan, Shahab Zareyan

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada
⨯
Shahab Zareyan ,

Contributed equally to this work with: Jianjia Fan, Shahab Zareyan

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada
⨯
Wenchen Zhao,

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada
⨯
Yoko Shimizu,

Affiliation Centre for Drug Research and Development, Vancouver, British Columbia, Canada
⨯
Tom A. Pfeifer,

Affiliation Centre for Drug Research and Development, Vancouver, British Columbia, Canada
⨯
Jun-Hyung Tak,

Affiliation Faculty of Land and Food Systems, University of British Columbia, Vancouver, British Columbia, Canada
⨯
Murray B. Isman,

Affiliation Faculty of Land and Food Systems, University of British Columbia, Vancouver, British Columbia, Canada
⨯
Bernard Van den Hoven,

Affiliation TC Scientific Inc., Edmonton, Alberta, Canada
⨯
Mark E. Duggan,

Affiliation AstraZeneca, Cambridge, Massachusetts, United States of America
⨯
Michael W. Wood,

Affiliation AstraZeneca, Cambridge, Massachusetts, United States of America
⨯
Cheryl L. Wellington ,

* E-mail: wcheryl@mail.ubc.ca

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada
⨯
Iva Kulic

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, Djavad Mowafaghian Centre for Brain Health, Vancouver, British Columbia, Canada

http://orcid.org/0000-0001-9093-113X

⨯

Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes

Jianjia Fan,
Shahab Zareyan,
Wenchen Zhao,
Yoko Shimizu,
Tom A. Pfeifer,
Jun-Hyung Tak,
Murray B. Isman,
Bernard Van den Hoven,
Mark E. Duggan,
Michael W. Wood

Published: September 6, 2016
https://doi.org/10.1371/journal.pone.0162384

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