Long-Term Moderate Oxidative Stress Decreased Ovarian Reproductive Function by Reducing Follicle Quality and Progesterone Production

Liangyan Shi; Jinjin Zhang; Zhiwen Lai; Yong Tian; Li Fang; Meng Wu; Jiaqiang Xiong; Xian Qin; Aiyue Luo; Shixuan Wang

doi:10.1371/journal.pone.0162194

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Open Access

Peer-reviewed

Research Article

Long-Term Moderate Oxidative Stress Decreased Ovarian Reproductive Function by Reducing Follicle Quality and Progesterone Production

Liangyan Shi ,

Contributed equally to this work with: Liangyan Shi, Jinjin Zhang

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Jinjin Zhang ,

Contributed equally to this work with: Liangyan Shi, Jinjin Zhang

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Zhiwen Lai,

Affiliation Maternal and Child Health Hospital of Zigong, Sichuan, 643000, China
⨯
Yong Tian,

Affiliation The Central Hospital of Enshi Autonomous Prefecture, 158 Wuyang Road, Enshi Autonomous Prefecture, Hubei, 445000, China
⨯
Li Fang,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Meng Wu,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Jiaqiang Xiong,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Xian Qin,

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Aiyue Luo ,

* E-mail: sxwang@tjh.tjmu.edu.cn (SW); aiyueluo@163.com (AL)

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Shixuan Wang

* E-mail: sxwang@tjh.tjmu.edu.cn (SW); aiyueluo@163.com (AL)

Affiliation Department of Obstetrics and Gynecology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯

Long-Term Moderate Oxidative Stress Decreased Ovarian Reproductive Function by Reducing Follicle Quality and Progesterone Production

Liangyan Shi,
Jinjin Zhang,
Zhiwen Lai,
Yong Tian,
Li Fang,
Meng Wu,
Jiaqiang Xiong,
Xian Qin,
Aiyue Luo,
Shixuan Wang

Published: September 27, 2016
https://doi.org/10.1371/journal.pone.0162194

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