The Deficiency of Indoleamine 2,3-Dioxygenase Aggravates the CCl4-Induced Liver Fibrosis in Mice

Hideyuki Ogiso; Hiroyasu Ito; Tatsuya Ando; Yuko Arioka; Ayumu Kanbe; Kazuki Ando; Tetsuya Ishikawa; Kuniaki Saito; Akira Hara; Hisataka Moriwaki; Masahito Shimizu; Mitsuru Seishima

doi:10.1371/journal.pone.0162183

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Open Access

Peer-reviewed

Research Article

The Deficiency of Indoleamine 2,3-Dioxygenase Aggravates the CCl₄-Induced Liver Fibrosis in Mice

Hideyuki Ogiso,

Affiliation Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
⨯
Hiroyasu Ito ,

* E-mail: hito@gifu-u.ac.jp

Affiliation Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
⨯
Tatsuya Ando,

Affiliation Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
⨯
Yuko Arioka,

Affiliation Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
⨯
Ayumu Kanbe,

Affiliation Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
⨯
Kazuki Ando,

Affiliation Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
⨯
Tetsuya Ishikawa,

Affiliation Department of Medical Technology, Nagoya University School of Health Sciences, Nagoya, Japan
⨯
Kuniaki Saito,

Affiliation Human Health Sciences, Kyoto University Graduate School of Medicine and Faculty of Medicine, Kyoto, Japan
⨯
Akira Hara,

Affiliation Department of Tumor Pathology, Gifu University Graduate School of Medicine, Gifu, Japan
⨯
Hisataka Moriwaki,

Affiliation First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
⨯
Masahito Shimizu,

Affiliation First Department of Internal Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
⨯
Mitsuru Seishima

Affiliation Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Gifu, Japan
⨯

The Deficiency of Indoleamine 2,3-Dioxygenase Aggravates the CCl₄-Induced Liver Fibrosis in Mice

Hideyuki Ogiso,
Hiroyasu Ito,
Tatsuya Ando,
Yuko Arioka,
Ayumu Kanbe,
Kazuki Ando,
Tetsuya Ishikawa,
Kuniaki Saito,
Akira Hara,
Hisataka Moriwaki

Published: September 6, 2016
https://doi.org/10.1371/journal.pone.0162183

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