High IFN-γ Release and Impaired Capacity of Multi-Cytokine Secretion in IGRA Supernatants Are Associated with Active Tuberculosis

Séverine Carrère-Kremer; Pierre-Alain Rubbo; Amandine Pisoni; Sophie Bendriss; Grégory Marin; Marianne Peries; Karine Bolloré; Dominique Terru; Sylvain Godreuil; Arnaud Bourdin; Philippe Van de Perre; Edouard Tuaillon

doi:10.1371/journal.pone.0162137

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Open Access

Peer-reviewed

Research Article

High IFN-γ Release and Impaired Capacity of Multi-Cytokine Secretion in IGRA Supernatants Are Associated with Active Tuberculosis

Séverine Carrère-Kremer ,

Contributed equally to this work with: Séverine Carrère-Kremer, Pierre-Alain Rubbo

* E-mail: severine.kremer@yahoo.fr (SCK); e-tuaillon@chu-montpellier.fr (ET)

Affiliations UMR1058 INSERM/University Montpellier/EFS, Montpellier, France, University Montpellier, Montpellier, France
⨯
Pierre-Alain Rubbo ,

Contributed equally to this work with: Séverine Carrère-Kremer, Pierre-Alain Rubbo

Affiliations UMR1058 INSERM/University Montpellier/EFS, Montpellier, France, University Montpellier, Montpellier, France
⨯
Amandine Pisoni,

Affiliations UMR1058 INSERM/University Montpellier/EFS, Montpellier, France, CHRU Montpellier, Departments of Bacteriology-Virology, Montpellier, France
⨯
Sophie Bendriss,

Affiliation CHRU Montpellier, Departments of Bacteriology-Virology, Montpellier, France
⨯
Grégory Marin,

Affiliation CHRU Montpellier, Department of Medical Information, Montpellier, France
⨯
Marianne Peries,

Affiliation UMR1058 INSERM/University Montpellier/EFS, Montpellier, France
⨯
Karine Bolloré,

Affiliations UMR1058 INSERM/University Montpellier/EFS, Montpellier, France, University Montpellier, Montpellier, France
⨯
Dominique Terru,

Affiliation CHRU Montpellier, Departments of Bacteriology-Virology, Montpellier, France
⨯
Sylvain Godreuil,

Affiliation CHRU Montpellier, Departments of Bacteriology-Virology, Montpellier, France
⨯
Arnaud Bourdin,

Affiliation CHRU Montpellier, Department of Pneumology, Montpellier, France
⨯
Philippe Van de Perre,

Affiliations UMR1058 INSERM/University Montpellier/EFS, Montpellier, France, University Montpellier, Montpellier, France, CHRU Montpellier, Departments of Bacteriology-Virology, Montpellier, France
⨯
Edouard Tuaillon

* E-mail: severine.kremer@yahoo.fr (SCK); e-tuaillon@chu-montpellier.fr (ET)

Affiliations UMR1058 INSERM/University Montpellier/EFS, Montpellier, France, University Montpellier, Montpellier, France, CHRU Montpellier, Departments of Bacteriology-Virology, Montpellier, France
⨯

High IFN-γ Release and Impaired Capacity of Multi-Cytokine Secretion in IGRA Supernatants Are Associated with Active Tuberculosis

Séverine Carrère-Kremer,
Pierre-Alain Rubbo,
Amandine Pisoni,
Sophie Bendriss,
Grégory Marin,
Marianne Peries,
Karine Bolloré,
Dominique Terru,
Sylvain Godreuil,
Arnaud Bourdin

Published: September 7, 2016
https://doi.org/10.1371/journal.pone.0162137

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