Regulatory CD4+ T-Cell Subsets and Anti-Citrullinated Protein Antibody Repertoire: Potential Biomarkers for Arthritis Development in Seropositive Arthralgia Patients?

• Koen M. J. Janssen,

  Affiliation Department of Oral and Maxillofacial Surgery, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands

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• Johanna Westra,

  Affiliation Department of Rheumatology and Clinical Immunology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands

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• Paulina Chalan,

  Affiliation Department of Rheumatology and Clinical Immunology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands

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• Annemieke M. H. Boots,

  Affiliation Department of Rheumatology and Clinical Immunology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands

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• Menke J. de Smit,

  Affiliation Center for Dentistry and Oral Hygiene, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands

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• Arie Jan van Winkelhoff,

  Affiliations Center for Dentistry and Oral Hygiene, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands, Department of Medical Microbiology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands

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• Arjan Vissink,

  Affiliation Department of Oral and Maxillofacial Surgery, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands

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• Elisabeth Brouwer

  * E-mail: e.brouwer@umcg.nl

  Affiliation Department of Rheumatology and Clinical Immunology, University of Groningen and University Medical Center Groningen, Groningen, The Netherlands

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