Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes

• Waseem K. Raja,

  Affiliation Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States of America

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• Alison E. Mungenast,

  Affiliation Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States of America

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• Yuan-Ta Lin,

  Affiliation Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States of America

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• Tak Ko,

  Affiliation Induced Pluripotent Stem Cell Core Facility, Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, MA, United States of America

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• Fatema Abdurrob,

  Affiliation Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States of America

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• Jinsoo Seo,

  Affiliation Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States of America

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• Li-Huei Tsai

  * E-mail: lhtsai@mit.edu

  Affiliation Picower Institute for Learning and Memory, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, United States of America

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