IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae

Kruthika Sundaram; Mohd. Akhlakur Rahman; Srabani Mitra; Daren L. Knoell; Shireen A. Woodiga; Samantha J. King; Mark D. Wewers

doi:10.1371/journal.pone.0161931

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Peer-reviewed

Research Article

IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae

Kruthika Sundaram,

Affiliation Pulmonary, Allergy, Critical Care and Sleep Medicine, Davis Heart and Lung Research Institute, Department of Internal Medicine, Ohio State University Medical Center, Columbus, Ohio, United States of America
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Mohd. Akhlakur Rahman,

Affiliations Department of Pharmacy, College of Pharmacy, Ohio State University, Columbus, Ohio, United States of America, Center for Microbial Interface Biology, Ohio State University, Columbus, Ohio, United States of America
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Srabani Mitra,

Affiliation Pulmonary, Allergy, Critical Care and Sleep Medicine, Davis Heart and Lung Research Institute, Department of Internal Medicine, Ohio State University Medical Center, Columbus, Ohio, United States of America
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Daren L. Knoell,

Affiliations Department of Pharmacy, College of Pharmacy, Ohio State University, Columbus, Ohio, United States of America, Center for Microbial Interface Biology, Ohio State University, Columbus, Ohio, United States of America
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Shireen A. Woodiga,

Affiliations Center for Microbial Interface Biology, Ohio State University, Columbus, Ohio, United States of America, Center for Microbial Pathogenesis, Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America
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Samantha J. King,

Affiliations Center for Microbial Interface Biology, Ohio State University, Columbus, Ohio, United States of America, Center for Microbial Pathogenesis, Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States of America, Department of Pediatrics, Ohio State University, Columbus, Ohio, United States of America
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Mark D. Wewers

* E-mail: wewers.2@osu.edu

Affiliations Pulmonary, Allergy, Critical Care and Sleep Medicine, Davis Heart and Lung Research Institute, Department of Internal Medicine, Ohio State University Medical Center, Columbus, Ohio, United States of America, Center for Microbial Interface Biology, Ohio State University, Columbus, Ohio, United States of America

http://orcid.org/0000-0002-7079-5633

⨯

IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae

Kruthika Sundaram,
Mohd. Akhlakur Rahman,
Srabani Mitra,
Daren L. Knoell,
Shireen A. Woodiga,
Samantha J. King,
Mark D. Wewers

Published: September 6, 2016
https://doi.org/10.1371/journal.pone.0161931

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Monocytes
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Pneumococcus
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Immunoblotting
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Immune response
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Protein expression
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