Hyaluronan Oligosaccharides Induce MMP-1 and -3 via Transcriptional Activation of NF-κB and p38 MAPK in Rheumatoid Synovial Fibroblasts

Open Access

Peer-reviewed

Research Article

Masahiro Hanabayashi,

Affiliation Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
⨯
Nobunori Takahashi ,

* E-mail: nobunori@med.nagoya-u.ac.jp

Affiliation Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
⨯
Yasumori Sobue,

Affiliation Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
⨯
Shinya Hirabara,

Affiliation Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
⨯
Naoki Ishiguro,

Affiliation Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
⨯
Toshihisa Kojima

Affiliation Department of Orthopedic Surgery and Rheumatology, Nagoya University Graduate School of Medicine, Nagoya, Japan
⨯

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Transcription factors
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Toll-like receptors
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Skeletal joints
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CD coreceptors
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MAPK signaling cascades
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Antibody therapy
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Extracellular matrix
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Fibroblasts
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