Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis

• Lei Zhang ,

  Contributed equally to this work with: Lei Zhang, Michael Ferreyros

  Affiliation Department of Dermatology and Charles C. Gates Center for Regenerative Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America

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• Michael Ferreyros ,

  Contributed equally to this work with: Lei Zhang, Michael Ferreyros

  Affiliation Department of Dermatology and Charles C. Gates Center for Regenerative Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America

  http://orcid.org/0000-0003-0418-7872

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• Weiguo Feng,

  Affiliation Department of Craniofacial Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America

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• Melanie Hupe,

  Affiliation Department of Dermatology, School of Medicine, University of California San Francisco, and Veterans Affairs Medical Center, San Francisco, CA, United States of America

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• Debra A. Crumrine,

  Affiliation Department of Dermatology, School of Medicine, University of California San Francisco, and Veterans Affairs Medical Center, San Francisco, CA, United States of America

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• Jiang Chen,

  Affiliation Department of Pathology and Dermatology, Stony Brook University School of Medicine, Stony Brook, NY, United States of America

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• Peter M. Elias,

  Affiliation Department of Dermatology, School of Medicine, University of California San Francisco, and Veterans Affairs Medical Center, San Francisco, CA, United States of America

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• Walter M. Holleran,

  Affiliation Department of Dermatology, School of Medicine, University of California San Francisco, and Veterans Affairs Medical Center, San Francisco, CA, United States of America

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• Lee Niswander,

  Affiliation Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America

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• Daniel Hohl,

  Affiliation Service de Dermatologie et Vénéréologie, Hôpital de Beaumont, Université de Lausanne, Lausanne, Switzerland

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• Trevor Williams ,

  * E-mail: Trevor.Williams@ucdenver.edu (TW); Enrique.Torchia@ucdenver.edu (ET); Dennis.Roop@ucdenver.edu (DR)

  Affiliation Department of Craniofacial Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America

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• Enrique C. Torchia ,

  * E-mail: Trevor.Williams@ucdenver.edu (TW); Enrique.Torchia@ucdenver.edu (ET); Dennis.Roop@ucdenver.edu (DR)

  Affiliation Department of Dermatology and Charles C. Gates Center for Regenerative Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America

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• Dennis R. Roop

  * E-mail: Trevor.Williams@ucdenver.edu (TW); Enrique.Torchia@ucdenver.edu (ET); Dennis.Roop@ucdenver.edu (DR)

  Affiliation Department of Dermatology and Charles C. Gates Center for Regenerative Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America

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