Tyrosine Binding Protein Sites Regulate the Intracellular Trafficking and Processing of Amyloid Precursor Protein through a Novel Lysosome-Directed Pathway

• Joshua H. K. Tam,

  Affiliations J. Allyn Taylor Centre for Cell Biology, Molecular Medicine Research Group, Robarts Research Institute, Western University, London Ontario, Canada, N6A 5B7, Department of Physiology and Pharmacology, Western University, London, Ontario, Canada, N6A 5B7

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• M. Rebecca Cobb,

  Affiliation Program in Neuroscience, Western University, London, Ontario, Canada, N6A 5B7

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• Claudia Seah,

  Affiliation J. Allyn Taylor Centre for Cell Biology, Molecular Medicine Research Group, Robarts Research Institute, Western University, London Ontario, Canada, N6A 5B7

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• Stephen H. Pasternak

  * E-mail: spasternak@robarts.ca

  Affiliations J. Allyn Taylor Centre for Cell Biology, Molecular Medicine Research Group, Robarts Research Institute, Western University, London Ontario, Canada, N6A 5B7, Department of Physiology and Pharmacology, Western University, London, Ontario, Canada, N6A 5B7, Program in Neuroscience, Western University, London, Ontario, Canada, N6A 5B7, Department of Clinical Neurological Sciences, The Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada, N6A 5B7

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