Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography

Rozanna L. Slade; Federica Pisaneschi; Quang-De Nguyen; Graham Smith; Laurence Carroll; Alice Beckley; Maciej A. Kaliszczak; Eric O. Aboagye

doi:10.1371/journal.pone.0161427

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Peer-reviewed

Research Article

Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography

Rozanna L. Slade,

Affiliation Comprehensive Cancer Imaging Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, United Kingdom
⨯
Federica Pisaneschi,

Affiliation Comprehensive Cancer Imaging Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, United Kingdom
⨯
Quang-De Nguyen,

Affiliation Comprehensive Cancer Imaging Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, United Kingdom
⨯
Graham Smith,

Affiliation Comprehensive Cancer Imaging Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, United Kingdom
⨯
Laurence Carroll,

Affiliation Comprehensive Cancer Imaging Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, United Kingdom
⨯
Alice Beckley,

Affiliation Comprehensive Cancer Imaging Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, United Kingdom
⨯
Maciej A. Kaliszczak,

Affiliation Comprehensive Cancer Imaging Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, United Kingdom
⨯
Eric O. Aboagye

* E-mail: eric.aboagye@imperial.ac.uk

Affiliation Comprehensive Cancer Imaging Centre, Imperial College London, Faculty of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, United Kingdom
⨯

Identification of ABC Transporter Interaction of a Novel Cyanoquinoline Radiotracer and Implications for Tumour Imaging by Positron Emission Tomography

Rozanna L. Slade,
Federica Pisaneschi,
Quang-De Nguyen,
Graham Smith,
Laurence Carroll,
Alice Beckley,
Maciej A. Kaliszczak,
Eric O. Aboagye

Published: August 23, 2016
https://doi.org/10.1371/journal.pone.0161427

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Positron emission tomography
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Small interfering RNA
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Breast cancer
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Protein expression
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