Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy

Holly J. Garringer; Jose M. Irimia; Wei Li; Charles B. Goodwin; Briana Richine; Anthony Acton; Rebecca J. Chan; Munro Peacock; Barry B. Muhoberac; Bernardino Ghetti; Ruben Vidal

doi:10.1371/journal.pone.0161341

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Open Access

Peer-reviewed

Research Article

Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy

Holly J. Garringer ,

Contributed equally to this work with: Holly J. Garringer, Jose M. Irimia

Affiliation Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
⨯
Jose M. Irimia ,

Contributed equally to this work with: Holly J. Garringer, Jose M. Irimia

Affiliation Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
⨯
Wei Li,

Affiliation Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
⨯
Charles B. Goodwin,

Affiliation Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
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Briana Richine,

Affiliation Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
⨯
Anthony Acton,

Affiliation Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
⨯
Rebecca J. Chan,

Affiliation Department of Pediatrics, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
⨯
Munro Peacock,

Affiliation Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
⨯
Barry B. Muhoberac,

Affiliation Department of Chemistry and Chemical Biology, Indiana University-Purdue University Indianapolis, Indianapolis, Indianam 46202, United States of America
⨯
Bernardino Ghetti,

Affiliation Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
⨯
Ruben Vidal

* E-mail: rvidal@iupui.edu

Affiliation Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, 46202, United States of America
⨯

Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy

Holly J. Garringer,
Jose M. Irimia,
Wei Li,
Charles B. Goodwin,
Briana Richine,
Anthony Acton,
Rebecca J. Chan,
Munro Peacock,
Barry B. Muhoberac,
Bernardino Ghetti

Published: August 30, 2016
https://doi.org/10.1371/journal.pone.0161341

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