Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B

Kyle E. Korolowicz; Radhakrishnan P. Iyer; Stefanie Czerwinski; Manasa Suresh; Junming Yang; Seetharamaiyer Padmanabhan; Anjaneyulu Sheri; Rajendra K. Pandey; Jeffrey Skell; Judith K. Marquis; Bhaskar V. Kallakury; Robin D. Tucker; Stephan Menne

doi:10.1371/journal.pone.0161313

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Open Access

Peer-reviewed

Research Article

Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B

Kyle E. Korolowicz,

Affiliation Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America
⨯
Radhakrishnan P. Iyer,

Affiliation Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America
⨯
Stefanie Czerwinski,

Affiliation Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America
⨯
Manasa Suresh,

Affiliation Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America
⨯
Junming Yang,

Affiliation Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America
⨯
Seetharamaiyer Padmanabhan,

Affiliation Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America
⨯
Anjaneyulu Sheri,

Affiliation Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America
⨯
Rajendra K. Pandey,

Current address: Johnson & Johnson Inc., New Brunswick, NJ, 08933, United States of America

Affiliation Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America
⨯
Jeffrey Skell,

Affiliation Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America
⨯
Judith K. Marquis,

Affiliation Spring Bank Pharmaceuticals, Inc., Suite S-7, 113 Cedar Street, Milford, MA, 01757, United States of America
⨯
Bhaskar V. Kallakury,

Affiliation Department of Pathology, Georgetown University Medical Center, Washington, DC, 20057, United States of America
⨯
Robin D. Tucker,

Affiliation Department of Comparative Medicine, Georgetown University Medical Center, Washington, DC, 20057, United States of America
⨯
Stephan Menne

* E-mail: sm923@georgetown.edu

Affiliation Department of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, 20057, United States of America
⨯

Antiviral Efficacy and Host Innate Immunity Associated with SB 9200 Treatment in the Woodchuck Model of Chronic Hepatitis B

Kyle E. Korolowicz,
Radhakrishnan P. Iyer,
Stefanie Czerwinski,
Manasa Suresh,
Junming Yang,
Seetharamaiyer Padmanabhan,
Anjaneyulu Sheri,
Rajendra K. Pandey,
Jeffrey Skell,
Judith K. Marquis

Published: August 23, 2016
https://doi.org/10.1371/journal.pone.0161313

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