IDH1/2 Mutants Inhibit TET-Promoted Oxidation of RNA 5mC to 5hmC

Qiang Xu; Kai Wang; Lina Wang; Yuting Zhu; Guangyu Zhou; Dan Xie; Qingkai Yang

doi:10.1371/journal.pone.0161261

Loading metrics

Open Access

Peer-reviewed

Research Article

IDH1/2 Mutants Inhibit TET-Promoted Oxidation of RNA 5mC to 5hmC

Qiang Xu ,

Contributed equally to this work with: Qiang Xu, Kai Wang

Affiliation Department of Oncology, Second Affiliated Hospital, Institute of Cancer Stem Cell, DaLian Medical University, 9 Western Lvshun South Road, Dalian, Liaoning 116044, China
⨯
Kai Wang ,

Contributed equally to this work with: Qiang Xu, Kai Wang

Affiliation Department of Oncology, Second Affiliated Hospital, Institute of Cancer Stem Cell, DaLian Medical University, 9 Western Lvshun South Road, Dalian, Liaoning 116044, China
⨯
Lina Wang,

Affiliation Department of Oncology, Second Affiliated Hospital, Institute of Cancer Stem Cell, DaLian Medical University, 9 Western Lvshun South Road, Dalian, Liaoning 116044, China
⨯
Yuting Zhu,

Affiliation Department of Oncology, Second Affiliated Hospital, Institute of Cancer Stem Cell, DaLian Medical University, 9 Western Lvshun South Road, Dalian, Liaoning 116044, China
⨯
Guangyu Zhou,

Affiliation Department of Oncology, Second Affiliated Hospital, Institute of Cancer Stem Cell, DaLian Medical University, 9 Western Lvshun South Road, Dalian, Liaoning 116044, China
⨯
Dan Xie,

Affiliation Department of Oncology, Second Affiliated Hospital, Institute of Cancer Stem Cell, DaLian Medical University, 9 Western Lvshun South Road, Dalian, Liaoning 116044, China
⨯
Qingkai Yang

* E-mail: Yangqingkai@dmu.edu.cn

Affiliation Department of Oncology, Second Affiliated Hospital, Institute of Cancer Stem Cell, DaLian Medical University, 9 Western Lvshun South Road, Dalian, Liaoning 116044, China
⨯

IDH1/2 Mutants Inhibit TET-Promoted Oxidation of RNA 5mC to 5hmC

Qiang Xu,
Kai Wang,
Lina Wang,
Yuting Zhu,
Guangyu Zhou,
Dan Xie,
Qingkai Yang

Published: August 22, 2016
https://doi.org/10.1371/journal.pone.0161261

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

RNA analysis
Is the Subject Area "RNA analysis" applicable to this article?

Thanks for your feedback.
Oxidation
Is the Subject Area "Oxidation" applicable to this article?

Thanks for your feedback.
Nucleosides
Is the Subject Area "Nucleosides" applicable to this article?

Thanks for your feedback.
Messenger RNA
Is the Subject Area "Messenger RNA" applicable to this article?

Thanks for your feedback.
Transfection
Is the Subject Area "Transfection" applicable to this article?

Thanks for your feedback.
Carcinogenesis
Is the Subject Area "Carcinogenesis" applicable to this article?

Thanks for your feedback.
Ionization
Is the Subject Area "Ionization" applicable to this article?

Thanks for your feedback.
Hyperexpression techniques
Is the Subject Area "Hyperexpression techniques" applicable to this article?

Thanks for your feedback.