A Robust and Efficient Production and Purification Procedure of Recombinant Alzheimers Disease Methionine-Modified Amyloid-β Peptides

Marie Hoarau; Yannick Malbert; Romain Irague; Christelle Hureau; Peter Faller; Emmanuel Gras; Isabelle André; Magali Remaud-Siméon

doi:10.1371/journal.pone.0161209

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Peer-reviewed

Research Article

A Robust and Efficient Production and Purification Procedure of Recombinant Alzheimers Disease Methionine-Modified Amyloid-β Peptides

Marie Hoarau,

Affiliations Laboratoire d’Ingénierie des Systèmes Biologiques et Procédés, Université de Toulouse, CNRS, INRA, INSA, Toulouse, France, Laboratoire de Chimie de Coordination, CNRS, Université de Toulouse, INPT, Toulouse, France
⨯
Yannick Malbert ,

Contributed equally to this work with: Yannick Malbert, Romain Irague

Affiliation Laboratoire d’Ingénierie des Systèmes Biologiques et Procédés, Université de Toulouse, CNRS, INRA, INSA, Toulouse, France
⨯
Romain Irague ,

Contributed equally to this work with: Yannick Malbert, Romain Irague

Current address: Unité Fonctionnalité et Ingénierie des Protéines, CNRS, Université de Nantes, Nantes, France

Affiliation Laboratoire d’Ingénierie des Systèmes Biologiques et Procédés, Université de Toulouse, CNRS, INRA, INSA, Toulouse, France
⨯
Christelle Hureau ,

¶‡ These authors also contributed equally to this work.

Affiliation Laboratoire de Chimie de Coordination, CNRS, Université de Toulouse, INPT, Toulouse, France
⨯
Peter Faller ,

Current address: Institut de Chimie, UMR 7177, Université de Strasbourg, Strasbourg, France

¶‡ These authors also contributed equally to this work.

Affiliation Laboratoire de Chimie de Coordination, CNRS, Université de Toulouse, INPT, Toulouse, France
⨯
Emmanuel Gras ,

¶‡ These authors also contributed equally to this work.

Affiliation Laboratoire de Chimie de Coordination, CNRS, Université de Toulouse, INPT, Toulouse, France
⨯
Isabelle André ,

¶‡ These authors also contributed equally to this work.

Affiliation Laboratoire d’Ingénierie des Systèmes Biologiques et Procédés, Université de Toulouse, CNRS, INRA, INSA, Toulouse, France
⨯
Magali Remaud-Siméon

* E-mail: remaud@insa-toulouse.fr

¶‡ These authors also contributed equally to this work.

Affiliation Laboratoire d’Ingénierie des Systèmes Biologiques et Procédés, Université de Toulouse, CNRS, INRA, INSA, Toulouse, France
⨯

A Robust and Efficient Production and Purification Procedure of Recombinant Alzheimers Disease Methionine-Modified Amyloid-β Peptides

Marie Hoarau,
Yannick Malbert,
Romain Irague,
Christelle Hureau,
Peter Faller,
Emmanuel Gras,
Isabelle André,
Magali Remaud-Siméon

Published: August 17, 2016
https://doi.org/10.1371/journal.pone.0161209

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