Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge

• Diletta Magini,

  Current address: Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milano, Italy

  Affiliations Novartis Vaccines, S.r.l., Siena, Italy, Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena, Siena, Italy

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• Cinzia Giovani,

  Current address: GSK Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines, S.r.l., Siena, Italy

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• Simona Mangiavacchi,

  Current address: GSK Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines, S.r.l., Siena, Italy

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• Silvia Maccari,

  Current address: GSK Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines, S.r.l., Siena, Italy

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• Raffaella Cecchi,

  Current address: GSK Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines, S.r.l., Siena, Italy

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• Jeffrey B. Ulmer,

  Current address: GSK Vaccines Inc., Cambridge, MA, United States of America

  Affiliation Novartis Vaccines Inc., Cambridge, MA, United States of America

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• Ennio De Gregorio,

  Current address: GSK Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines, S.r.l., Siena, Italy

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• Andrew J. Geall,

  Current address: Avidity NanoMedicines LLC, San Diego, CA, United States of America

  Affiliation Novartis Vaccines Inc., Cambridge, MA, United States of America

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• Michela Brazzoli ,

  * E-mail: michela.x.brazzoli@gsk.com

  Current address: GSK Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines, S.r.l., Siena, Italy

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• Sylvie Bertholet

  Current address: GSK Vaccines S.r.l., Siena, Italy

  Affiliation Novartis Vaccines, S.r.l., Siena, Italy

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