Ligand Binding at the α4-α4 Agonist-Binding Site of the α4β2 nAChR Triggers Receptor Activation through a Pre-Activated Conformational State

• Dinesh C. Indurthi,

  Affiliation Faculty of Pharmacy, University of Sydney, NSW, 2006, Australia

  ⨯
• Trevor M. Lewis,

  Affiliation School of Medical Sciences, University of NSW, Kensington, NSW, 2052, Australia

  ⨯
• Philip K. Ahring,

  Affiliation Faculty of Pharmacy, University of Sydney, NSW, 2006, Australia

  ⨯
• Thomas Balle,

  Affiliation Faculty of Pharmacy, University of Sydney, NSW, 2006, Australia

  ⨯
• Mary Chebib ,

  * E-mail: nathan.absalom@sydney.edu.au (NLA); mary.collins@sydney.edu.au (MC)

  Affiliation Faculty of Pharmacy, University of Sydney, NSW, 2006, Australia

  ⨯
• Nathan L. Absalom

  * E-mail: nathan.absalom@sydney.edu.au (NLA); mary.collins@sydney.edu.au (MC)

  Affiliation Faculty of Pharmacy, University of Sydney, NSW, 2006, Australia

  ⨯