Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients

Steffen Dietz; Uwe Schirmer; Clémentine Mercé; Nikolas von Bubnoff; Edgar Dahl; Michael Meister; Thomas Muley; Michael Thomas; Holger Sültmann

doi:10.1371/journal.pone.0161012

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Open Access

Peer-reviewed

Research Article

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients

Steffen Dietz ,

Contributed equally to this work with: Steffen Dietz, Uwe Schirmer

Affiliations Cancer Genome Research Group, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, Heidelberg, Germany, Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany
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Uwe Schirmer ,

Contributed equally to this work with: Steffen Dietz, Uwe Schirmer

Affiliations Cancer Genome Research Group, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, Heidelberg, Germany, Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany
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Clémentine Mercé,

Affiliations Cancer Genome Research Group, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, Heidelberg, Germany, Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany
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Nikolas von Bubnoff,

Affiliations Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany, German Cancer Consortium (DKTK), Heidelberg, Germany
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Edgar Dahl,

Affiliation Molecular Oncology Group, Institute of Pathology, RWTH Aachen University, Aachen, Germany
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Michael Meister,

Affiliations Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany, Translational Research Unit, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany
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Thomas Muley,

Affiliations Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany, Translational Research Unit, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany
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Michael Thomas,

Affiliations Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany, Department of Oncology, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany
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Holger Sültmann

* E-mail: h.sueltmann@dkfz.de

Affiliations Cancer Genome Research Group, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, Heidelberg, Germany, Translational Lung Research Center (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany, German Cancer Consortium (DKTK), Heidelberg, Germany
⨯

Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients

Steffen Dietz,
Uwe Schirmer,
Clémentine Mercé,
Nikolas von Bubnoff,
Edgar Dahl,
Michael Meister,
Thomas Muley,
Michael Thomas,
Holger Sültmann

Published: August 16, 2016
https://doi.org/10.1371/journal.pone.0161012

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