Scalable Production of HPV16 L1 Protein and VLPs from Tobacco Leaves

Maryam Zahin; Joongho Joh; Sujita Khanal; Adam Husk; Hugh Mason; Heribert Warzecha; Shin-je Ghim; Donald M. Miller; Nobuyuki Matoba; Alfred Bennett Jenson

doi:10.1371/journal.pone.0160995

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Open Access

Peer-reviewed

Research Article

Scalable Production of HPV16 L1 Protein and VLPs from Tobacco Leaves

Maryam Zahin,

Affiliation James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America
⨯
Joongho Joh ,

* E-mail: j0joh001@louisville.edu

Affiliations James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America, Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America
⨯
Sujita Khanal,

Affiliations James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America, Department of Biochemistry and Molecular Genetics, University of Louisville, Louisville, Kentucky, United States of America
⨯
Adam Husk,

Affiliations James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America, Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America
⨯
Hugh Mason,

Affiliation Biodesign Institute and School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America
⨯
Heribert Warzecha,

Affiliation Plant Biotechnology and Metabolic Engineering, Technische Universita¨t Darmstadt, Schnittspahnstrasse 3–5, 64287, Darmstadt, Germany
⨯
Shin-je Ghim,

Affiliation James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America
⨯
Donald M. Miller,

Affiliations James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America, Department of Medicine, University of Louisville, Louisville, Kentucky, United States of America
⨯
Nobuyuki Matoba,

Affiliations James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America, Owensboro Cancer Research Program, Owensboro, Kentucky, United States of America, Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky, United States of America
⨯
Alfred Bennett Jenson

Affiliation James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, United States of America
⨯

Scalable Production of HPV16 L1 Protein and VLPs from Tobacco Leaves

Maryam Zahin,
Joongho Joh,
Sujita Khanal,
Adam Husk,
Hugh Mason,
Heribert Warzecha,
Shin-je Ghim,
Donald M. Miller,
Nobuyuki Matoba,
Alfred Bennett Jenson

Published: August 12, 2016
https://doi.org/10.1371/journal.pone.0160995

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17 Aug 2016
15:01 GMT
Most Recent

Chloroplast localisation Posted by edrybicki on 17 Aug 2016 at 09:35 GMT

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HPV-16
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Nicotiana
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Enzyme-linked immunoassays
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Leaves
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Protein extraction
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Chloroplasts
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Immunoblotting
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Insects
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