Commensal Bacteria-Induced Inflammasome Activation in Mouse and Human Macrophages Is Dependent on Potassium Efflux but Does Not Require Phagocytosis or Bacterial Viability

• Kejie Chen,

  Affiliations Mucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, United States of America, College of Veterinary Medicine, Sichuan Agricultural University, Ya’an, Sichuan, China

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• Nanda Kumar N. Shanmugam,

  Affiliation Mucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, United States of America

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• Michael A. Pazos,

  Affiliation Mucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, United States of America

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• Bryan P. Hurley,

  Affiliation Mucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, United States of America

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• Bobby J. Cherayil

  * E-mail: cherayil@helix.mgh.harvard.edu

  Affiliation Mucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, United States of America

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