IgM-Enriched Immunoglobulin Attenuates Systemic Endotoxin Activity in Early Severe Sepsis: A Before-After Cohort Study

Open Access

Peer-reviewed

Research Article

Saskia Wand ,

Contributed equally to this work with: Saskia Wand, Matthias Klages

* E-mail: saskia.wand@med.uni-goettingen.de

Current address: Clinic for Anaesthesiology, University Hospital Goettingen, Goettingen, Germany

Affiliations Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany, Clinic for Anaesthesiology, University Hospital Goettingen, Goettingen, Germany
⨯
Matthias Klages ,

Contributed equally to this work with: Saskia Wand, Matthias Klages

Affiliation Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Christin Kirbach,

Affiliation Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
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Joanna Warszawska,

Affiliation Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Patrick Meybohm,

Affiliation Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Kai Zacharowski,

Affiliation Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
⨯
Alexander Koch

Affiliation Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany
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Endotoxins
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Inflammation
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Antibodies
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Sepsis
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Severe sepsis
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Fibrinogen
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Platelets
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Viscoelasticity
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