Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics

• Andrew B. Waight,

  Affiliation Department of Protein Sciences, Seattle Genetics, Inc., Bothell, WA, United States of America

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• Katja Bargsten,

  Current address: Department of Biochemistry, University of Zurich, Zürich, Switzerland

  Affiliation Department of Biology and Chemistry, Laboratory of Biomolecular Research, Paul Scherrer Institut, Villigen PSI, Switzerland

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• Svetlana Doronina,

  Affiliation Department of Protein Sciences, Seattle Genetics, Inc., Bothell, WA, United States of America

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• Michel O. Steinmetz,

  Affiliation Department of Biology and Chemistry, Laboratory of Biomolecular Research, Paul Scherrer Institut, Villigen PSI, Switzerland

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• Django Sussman ,

  * E-mail: dsussman@seagen.com (DS); andrea.prota@psi.ch (AEP)

  Affiliation Department of Protein Sciences, Seattle Genetics, Inc., Bothell, WA, United States of America

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• Andrea E. Prota

  * E-mail: dsussman@seagen.com (DS); andrea.prota@psi.ch (AEP)

  Affiliation Department of Biology and Chemistry, Laboratory of Biomolecular Research, Paul Scherrer Institut, Villigen PSI, Switzerland

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