Culture and Drug Profiling of Patient Derived Malignant Pleural Effusions for Personalized Cancer Medicine

Christian Ruiz; Stefan Kustermann; Elina Pietilae; Tatjana Vlajnic; Betty Baschiera; Leila Arabi; Thomas Lorber; Martin Oeggerli; Spasenija Savic; Ellen Obermann; Thomas Singer; Sacha I. Rothschild; Alfred Zippelius; Adrian B. Roth; Lukas Bubendorf

doi:10.1371/journal.pone.0160807

Loading metrics

Open Access

Peer-reviewed

Research Article

Culture and Drug Profiling of Patient Derived Malignant Pleural Effusions for Personalized Cancer Medicine

Christian Ruiz ,

Contributed equally to this work with: Christian Ruiz, Stefan Kustermann

* E-mail: christian.ruiz@unibas.ch

Affiliation Institute for Pathology, University Hospital Basel, Basel, Switzerland
⨯
Stefan Kustermann ,

Contributed equally to this work with: Christian Ruiz, Stefan Kustermann

Affiliation Pharmaceutical Sciences, Roche Innovation Centre Basel, Basel, Switzerland
⨯
Elina Pietilae,

Affiliation Pharmaceutical Sciences, Roche Innovation Centre Basel, Basel, Switzerland
⨯
Tatjana Vlajnic,

Affiliation Institute for Pathology, University Hospital Basel, Basel, Switzerland
⨯
Betty Baschiera,

Affiliation Institute for Pathology, University Hospital Basel, Basel, Switzerland
⨯
Leila Arabi,

Current address: Nanotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran

Affiliation Institute for Pathology, University Hospital Basel, Basel, Switzerland
⨯
Thomas Lorber,

Affiliation Institute for Pathology, University Hospital Basel, Basel, Switzerland
⨯
Martin Oeggerli,

Affiliation Institute for Pathology, University Hospital Basel, Basel, Switzerland
⨯
Spasenija Savic,

Affiliation Institute for Pathology, University Hospital Basel, Basel, Switzerland
⨯
Ellen Obermann,

Affiliation Institute for Pathology, University Hospital Basel, Basel, Switzerland
⨯
Thomas Singer,

Affiliation Pharmaceutical Sciences, Roche Innovation Centre Basel, Basel, Switzerland
⨯
Sacha I. Rothschild,

Affiliation Department of Medical Oncology, University Hospital Basel, Basel, Switzerland
⨯
Alfred Zippelius,

Affiliation Department of Medical Oncology, University Hospital Basel, Basel, Switzerland
⨯
Adrian B. Roth ,

¶‡ These authors share senior authorship.

Affiliation Pharmaceutical Sciences, Roche Innovation Centre Basel, Basel, Switzerland
⨯
Lukas Bubendorf

¶‡ These authors share senior authorship.

Affiliation Institute for Pathology, University Hospital Basel, Basel, Switzerland
⨯

Culture and Drug Profiling of Patient Derived Malignant Pleural Effusions for Personalized Cancer Medicine

Christian Ruiz,
Stefan Kustermann,
Elina Pietilae,
Tatjana Vlajnic,
Betty Baschiera,
Leila Arabi,
Thomas Lorber,
Martin Oeggerli,
Spasenija Savic,
Ellen Obermann

Published: August 22, 2016
https://doi.org/10.1371/journal.pone.0160807

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Lung and intrathoracic tumors
Is the Subject Area "Lung and intrathoracic tumors" applicable to this article?

Thanks for your feedback.
Pleural effusion
Is the Subject Area "Pleural effusion" applicable to this article?

Thanks for your feedback.
Malignant tumors
Is the Subject Area "Malignant tumors" applicable to this article?

Thanks for your feedback.
Non-small cell lung cancer
Is the Subject Area "Non-small cell lung cancer" applicable to this article?

Thanks for your feedback.
Ovarian cancer
Is the Subject Area "Ovarian cancer" applicable to this article?

Thanks for your feedback.
Cancer genomics
Is the Subject Area "Cancer genomics" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.