HIF-2α Expression Regulates Sprout Formation into 3D Fibrin Matrices in Prolonged Hypoxia in Human Microvascular Endothelial Cells

Open Access

Peer-reviewed

Research Article

Tessa D. Nauta,

Affiliations Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1118 1081 HV, Amsterdam, The Netherlands, A-Skin Nederland BV, De Boelelaan 1117, Amsterdam 1007 MB, The Netherlands
⨯
Monique C. A. Duyndam,

Affiliation Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1118 1081 HV, Amsterdam, The Netherlands
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Ester M. Weijers,

Affiliations Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1118 1081 HV, Amsterdam, The Netherlands, A-Skin Nederland BV, De Boelelaan 1117, Amsterdam 1007 MB, The Netherlands
⨯
Victor M. W. van Hinsbergh,

Affiliation Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1118 1081 HV, Amsterdam, The Netherlands
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Pieter Koolwijk

* E-mail: p.koolwijk@vumc.nl

Affiliation Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1118 1081 HV, Amsterdam, The Netherlands
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Hypoxia
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Oxygen
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Endothelial cells
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Medical hypoxia
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Fibrin
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Angiogenesis
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Transfection
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Gene expression
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