Induction of Connective Tissue Growth Factor Expression by Hypoxia in Human Lung Fibroblasts via the MEKK1/MEK1/ERK1/GLI-1/GLI-2 and AP-1 Pathways

Open Access

Peer-reviewed

Research Article

Yi Cheng,

Affiliation School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Chien-huang Lin,

Affiliation Gradual Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Jing-Yun Chen,

Affiliation Gradual Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Chien-Hua Li,

Affiliation Gradual Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan
⨯
Yu-Tin Liu,

Affiliation School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan
⨯
Bing-Chang Chen

* E-mail: bcchen@tmu.edu.tw

Affiliations School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Small interfering RNA
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Hypoxia
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Medical hypoxia
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Fibroblasts
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Transfection
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Pulmonary fibrosis
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Collagens
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