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Open Access
Peer-reviewed
Research Article
Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery
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Daisuke Saigusa ,
* E-mail: saigusa@m.tohoku.ac.jp (DS); masiyamamoto@med.tohoku.ac.jp (MY)
Affiliations Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan, Medical Biochemistry, Tohoku University School of Medicine, Sendai, Miyagi, Japan, CREST, Japan Agency for Medical Research and Development (AMED), Chiyoda, Tokyo, Japan
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Yasunobu Okamura,
Affiliation Department of Systems Bioinformatics, Graduate School of Information Sciences, Tohoku University, Sendai, Miyagi, Japan
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Ikuko N. Motoike,
Affiliations Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan, Department of Systems Bioinformatics, Graduate School of Information Sciences, Tohoku University, Sendai, Miyagi, Japan
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Yasutake Katoh,
Affiliations Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan, Department of Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
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Yasuhiro Kurosawa,
Affiliation Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
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Reina Saijyo,
Affiliation Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan
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Seizo Koshiba,
Affiliations Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan, Medical Biochemistry, Tohoku University School of Medicine, Sendai, Miyagi, Japan
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Jun Yasuda,
Affiliation Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan
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Hozumi Motohashi,
Affiliations Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan, Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Miyagi, Japan
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Junichi Sugawara,
Affiliations Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan, Department of Gynecology and Obstetrics, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan
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Osamu Tanabe,
Affiliation Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan
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Kengo Kinoshita,
Affiliations Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan, Department of Systems Bioinformatics, Graduate School of Information Sciences, Tohoku University, Sendai, Miyagi, Japan
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Masayuki Yamamoto
* E-mail: saigusa@m.tohoku.ac.jp (DS); masiyamamoto@med.tohoku.ac.jp (MY)
Affiliations Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan, Medical Biochemistry, Tohoku University School of Medicine, Sendai, Miyagi, Japan
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Establishment of Protocols for Global Metabolomics by LC-MS for Biomarker Discovery
- Daisuke Saigusa,
- Yasunobu Okamura,
- Ikuko N. Motoike,
- Yasutake Katoh,
- Yasuhiro Kurosawa,
- Reina Saijyo,
- Seizo Koshiba,
- Jun Yasuda,
- Hozumi Motohashi,
- Junichi Sugawara
- Published: August 31, 2016
- https://doi.org/10.1371/journal.pone.0160555