Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity

Open Access

Peer-reviewed

Research Article

Nina Marie Pedersen,

Affiliations Centre for Cancer Biomedicine, Faculty of Medicine, Oslo University Hospital, Oslo, Norway, Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
⨯
Tor Espen Thorvaldsen,

Affiliations Centre for Cancer Biomedicine, Faculty of Medicine, Oslo University Hospital, Oslo, Norway, Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
⨯
Sebastian Wolfgang Schultz,

Affiliations Centre for Cancer Biomedicine, Faculty of Medicine, Oslo University Hospital, Oslo, Norway, Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
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Eva Maria Wenzel ,

* E-mail: eva.wenzel@rr-research.no (EMW); stenmark@ulrik.uio.no (HS)

Affiliations Centre for Cancer Biomedicine, Faculty of Medicine, Oslo University Hospital, Oslo, Norway, Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
⨯
Harald Stenmark

* E-mail: eva.wenzel@rr-research.no (EMW); stenmark@ulrik.uio.no (HS)

Affiliations Centre for Cancer Biomedicine, Faculty of Medicine, Oslo University Hospital, Oslo, Norway, Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
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SW480 cells
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Proteasomes
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Proteasome inhibitors
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Immunoprecipitation
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Colorectal cancer
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Messenger RNA
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Phosphorylation
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Small interfering RNA
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