WNT2 Promotes Cervical Carcinoma Metastasis and Induction of Epithelial-Mesenchymal Transition

Yun Zhou; Yongwen Huang; Xinping Cao; Jing Xu; Lan Zhang; Jianhua Wang; Long Huang; Shuting Huang; Linjing Yuan; Weihua Jia; Xingjuan Yu; Rongzhen Luo; Min Zheng

doi:10.1371/journal.pone.0160414

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Research Article

WNT2 Promotes Cervical Carcinoma Metastasis and Induction of Epithelial-Mesenchymal Transition

Yun Zhou ,

Contributed equally to this work with: Yun Zhou, Yongwen Huang, Xinping Cao

Affiliations Department of Gynecology, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Yongwen Huang ,

Contributed equally to this work with: Yun Zhou, Yongwen Huang, Xinping Cao

Affiliations Department of Gynecology, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Xinping Cao ,

Contributed equally to this work with: Yun Zhou, Yongwen Huang, Xinping Cao

Affiliations Department of Radiotherapy, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Jing Xu,

Affiliations State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Lan Zhang,

Affiliations Department of Gynecology, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Jianhua Wang,

Affiliation Cardiovascular Department, Second People's Hospital of Guangdong Province, 1 Shi-liu gang Road East, Guangzhou, 510317, P. R. China
⨯
Long Huang,

Affiliation Department of Oncology, the Second Affiliated Hospital, Nanchang University, Nanchang, 330000, P. R. China
⨯
Shuting Huang,

Affiliations Department of Gynecology, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Linjing Yuan,

Affiliations Department of Gynecology, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Weihua Jia,

Affiliations State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Xingjuan Yu,

Affiliations State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Rongzhen Luo,

Affiliations Department of Pathology, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯
Min Zheng

* E-mail: zhengmin@sysucc.org.cn

Affiliations Department of Gynecology, Sun Yat-Sen University Cancer Center, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, State Key Laboratory of Oncology in South China, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China, Collaborative Innovation Center for Cancer Medicine, 651 Dongfeng Road East, Guangzhou, Guangzhou, 510060, P. R. China
⨯

WNT2 Promotes Cervical Carcinoma Metastasis and Induction of Epithelial-Mesenchymal Transition

Yun Zhou,
Yongwen Huang,
Xinping Cao,
Jing Xu,
Lan Zhang,
Jianhua Wang,
Long Huang,
Shuting Huang,
Linjing Yuan,
Weihua Jia

Published: August 11, 2016
https://doi.org/10.1371/journal.pone.0160414

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