E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment

Ningning Wang; Yiping Wu; Ning Zeng; Haiping Wang; Pei Deng; Yi Xu; Youping Feng; Hong Zeng; Hongxia Yang; Kai Hou; Andrew Wang; Keshav Parthasarathy; Samaksh Goyal; Gangjian Qin; Min Wu

doi:10.1371/journal.pone.0160411

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Open Access

Peer-reviewed

Research Article

E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment

Ningning Wang ,

Contributed equally to this work with: Ningning Wang, Yiping Wu

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Yiping Wu ,

Contributed equally to this work with: Ningning Wang, Yiping Wu

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Ning Zeng,

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Haiping Wang,

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Pei Deng,

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Yi Xu,

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Youping Feng,

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Hong Zeng,

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Hongxia Yang,

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Kai Hou,

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯
Andrew Wang,

Affiliation College of Liberal Arts and Science, University of Illinois Urbana-Champaign, Illinois, United States of America
⨯
Keshav Parthasarathy,

Affiliation Feinberg Cardiovascular Research Institute, Department of Medicine – Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯
Samaksh Goyal,

Affiliation Feinberg Cardiovascular Research Institute, Department of Medicine – Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America
⨯
Gangjian Qin,

Affiliations Feinberg Cardiovascular Research Institute, Department of Medicine – Cardiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Department of Biomedical Engineering, the University of Alabama at Birmingham, School of Medicine and School of Engineering, Birmingham, Alabama, United States of America
⨯
Min Wu

* E-mail: wumin82@hotmail.com

Affiliation Department of Plastic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
⨯

E2F1 Hinders Skin Wound Healing by Repressing Vascular Endothelial Growth Factor (VEGF) Expression, Neovascularization, and Macrophage Recruitment

Ningning Wang,
Yiping Wu,
Ning Zeng,
Haiping Wang,
Pei Deng,
Yi Xu,
Youping Feng,
Hong Zeng,
Hongxia Yang,
Kai Hou

Published: August 4, 2016
https://doi.org/10.1371/journal.pone.0160411

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