Identification of Novel Smoothened Ligands Using Structure-Based Docking

• Celine Lacroix ,

  Contributed equally to this work with: Celine Lacroix, Inbar Fish

  Affiliation Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada

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• Inbar Fish ,

  Contributed equally to this work with: Celine Lacroix, Inbar Fish

  Affiliations Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America, Department of Biochemistry and Molecular Biology, George S. Wise Faculty of Life Sciences, Tel-Aviv University, Ramat Aviv, Israel

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• Hayarpi Torosyan,

  Affiliation Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

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• Pranavan Parathaman,

  Affiliation Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada

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• John J. Irwin,

  Affiliation Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

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• Brian K. Shoichet ,

  * E-mail: bshoichet@gmail.com (BS); stephane.angers@utoronto.ca (SA)

  Affiliation Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California, United States of America

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• Stephane Angers

  * E-mail: bshoichet@gmail.com (BS); stephane.angers@utoronto.ca (SA)

  Affiliations Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada, Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

  http://orcid.org/0000-0001-7241-9044

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