Evaluation of the PPAR-γ Agonist Pioglitazone in Mild Asthma: A Double-Blind Randomized Controlled Trial

J. R. Anderson; K. Mortimer; L. Pang; K. M Smith; H. Bailey; D. B. Hodgson; D. E. Shaw; A. J. Knox; T. W. Harrison

doi:10.1371/journal.pone.0160257

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Open Access

Peer-reviewed

Research Article

Evaluation of the PPAR-γ Agonist Pioglitazone in Mild Asthma: A Double-Blind Randomized Controlled Trial

J. R. Anderson,

Affiliation Nottingham Respiratory Research Unit, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham, NG5 1PB, United Kingdom
⨯
K. Mortimer ,

* E-mail: kevin.mortimer@lstmed.ac.uk

Affiliation Liverpool School of Tropical Medicine, Liverpool, UK and Aintree University Hospital NHS Foundation Trust, Fazakerley, United Kingdom

http://orcid.org/0000-0002-8118-8871

⨯
L. Pang,

Affiliation Nottingham Respiratory Research Unit, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham, NG5 1PB, United Kingdom
⨯
K. M Smith,

Affiliation Nottingham Respiratory Research Unit, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham, NG5 1PB, United Kingdom
⨯
H. Bailey,

Affiliation Nottingham Respiratory Research Unit, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham, NG5 1PB, United Kingdom
⨯
D. B. Hodgson,

Affiliation Nottingham Respiratory Research Unit, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham, NG5 1PB, United Kingdom
⨯
D. E. Shaw,

Affiliation Nottingham Respiratory Research Unit, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham, NG5 1PB, United Kingdom
⨯
A. J. Knox,

Affiliation Nottingham Respiratory Research Unit, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham, NG5 1PB, United Kingdom
⨯
T. W. Harrison

Affiliation Nottingham Respiratory Research Unit, University of Nottingham, Clinical Sciences Building, City Hospital, Hucknall Road, Nottingham, NG5 1PB, United Kingdom
⨯

Evaluation of the PPAR-γ Agonist Pioglitazone in Mild Asthma: A Double-Blind Randomized Controlled Trial

J. R. Anderson,
K. Mortimer,
L. Pang,
K. M Smith,
H. Bailey,
D. B. Hodgson,
D. E. Shaw,
A. J. Knox,
T. W. Harrison

Published: August 25, 2016
https://doi.org/10.1371/journal.pone.0160257

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