Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile

• Rami A. Al-Horani,

  Affiliation Department of Medicinal Chemistry & Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, Virginia, United States of America

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• Rajesh Karuturi,

  Current address: Biogene Organics, Raleigh, North Carolina, United States of America

  Affiliation Department of Medicinal Chemistry & Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, Virginia, United States of America

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• Michael Lee,

  Affiliation Department of Medicinal Chemistry & Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, Virginia, United States of America

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• Daniel K. Afosah,

  Affiliation Department of Medicinal Chemistry & Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, Virginia, United States of America

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• Umesh R. Desai

  * E-mail: urdesai@vcu.edu

  Affiliation Department of Medicinal Chemistry & Institute for Structural Biology, Drug Discovery and Development, Virginia Commonwealth University, Richmond, Virginia, United States of America

  http://orcid.org/0000-0002-1976-6597

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