Schedule-Dependent Antiangiogenic and Cytotoxic Effects of Chemotherapy on Vascular Endothelial and Retinoblastoma Cells

Ursula Winter; Hebe A. Mena; Soledad Negrotto; Eloisa Arana; Guillem Pascual-Pasto; Viviana Laurent; Mariona Suñol; Guillermo L. Chantada; Angel M. Carcaboso; Paula Schaiquevich

doi:10.1371/journal.pone.0160094

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Peer-reviewed

Research Article

Schedule-Dependent Antiangiogenic and Cytotoxic Effects of Chemotherapy on Vascular Endothelial and Retinoblastoma Cells

Ursula Winter,

Affiliations Clinical Pharmacokinetics Unit, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina, National Scientific and Technical Research Council, CONICET, Buenos Aires, Argentina
⨯
Hebe A. Mena,

Affiliation Experimental Thrombosis Laboratory, IMEX, National Academy of Medicine, Buenos Aires, Argentina
⨯
Soledad Negrotto,

Affiliations National Scientific and Technical Research Council, CONICET, Buenos Aires, Argentina, Experimental Thrombosis Laboratory, IMEX, National Academy of Medicine, Buenos Aires, Argentina
⨯
Eloisa Arana,

Affiliations National Scientific and Technical Research Council, CONICET, Buenos Aires, Argentina, Inmunogenetics Laboratory, INIGEM, University of Buenos Aires, Buenos Aires, Argentina
⨯
Guillem Pascual-Pasto,

Affiliation Developmental tumor biology Laboratory and Department of Pediatric Hematology and Oncology, Hospital Sant Joan de Deu, Barcelona, Spain
⨯
Viviana Laurent,

Affiliation Clinical Pharmacokinetics Unit, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina
⨯
Mariona Suñol,

Affiliation Pathology, Hospital Sant Joan de Deu, Barcelona, Spain
⨯
Guillermo L. Chantada,

Affiliations National Scientific and Technical Research Council, CONICET, Buenos Aires, Argentina, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina
⨯
Angel M. Carcaboso,

Affiliation Developmental tumor biology Laboratory and Department of Pediatric Hematology and Oncology, Hospital Sant Joan de Deu, Barcelona, Spain
⨯
Paula Schaiquevich

* E-mail: paulas@conicet.gov.ar

Affiliations Clinical Pharmacokinetics Unit, Hospital de Pediatría JP Garrahan, Buenos Aires, Argentina, National Scientific and Technical Research Council, CONICET, Buenos Aires, Argentina
⨯

Schedule-Dependent Antiangiogenic and Cytotoxic Effects of Chemotherapy on Vascular Endothelial and Retinoblastoma Cells

Ursula Winter,
Hebe A. Mena,
Soledad Negrotto,
Eloisa Arana,
Guillem Pascual-Pasto,
Viviana Laurent,
Mariona Suñol,
Guillermo L. Chantada,
Angel M. Carcaboso,
Paula Schaiquevich

Published: July 28, 2016
https://doi.org/10.1371/journal.pone.0160094

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