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Open Access
Peer-reviewed
Research Article
Bacterial Loads Measured by the Xpert MTB/RIF Assay as Markers of Culture Conversion and Bacteriological Cure in Pulmonary TB
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Shubhada Shenai,
Affiliation Division of Infectious Diseases, Rutgers New Jersey Medical School, ^Rutgers Biomedical & Health Sciences (Formerly UMDNJ), 185 South Orange Avenue, Newark, New Jersey, United States of America
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Katharina Ronacher,
Affiliation DST/NRF Centre of Excellence for Biomedical TB Research and MRC Centre for TB Research, Division of Molecular Biology & Human Genetics, Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Stellenbosch University, Cape Town, South Africa
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Stefanus Malherbe,
Affiliation DST/NRF Centre of Excellence for Biomedical TB Research and MRC Centre for TB Research, Division of Molecular Biology & Human Genetics, Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Stellenbosch University, Cape Town, South Africa
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Kim Stanley,
Affiliation DST/NRF Centre of Excellence for Biomedical TB Research and MRC Centre for TB Research, Division of Molecular Biology & Human Genetics, Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Stellenbosch University, Cape Town, South Africa
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Magdalena Kriel,
Affiliation DST/NRF Centre of Excellence for Biomedical TB Research and MRC Centre for TB Research, Division of Molecular Biology & Human Genetics, Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Stellenbosch University, Cape Town, South Africa
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Jill Winter,
Affiliation Catalysis Foundation for Health, Emeryville, California, United States of America
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Thomas Peppard,
Affiliation Certara, LP, on contract to the Bill and Melinda Gates Foundation, Greater Detroit Area, United States of America
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Charles E. Barry,
Affiliation Brown University, Providence Rhode Islands, United States of America
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Jing Wang,
Affiliation Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., NCI Campus at Frederick, Frederick, Maryland, United States of America
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Lori E. Dodd,
Affiliation Biostatistics Research Branch, NIAID, NIH, Bethesda, Maryland, United States of America
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Laura E. Via,
Affiliations Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, NIAID, National Institutes of Health, Bethesda, Maryland, United States of America, Institute of Infectious Disease and Molecular Medicine, and the Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Rondebosch 7701, South Africa
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Clifton E. Barry 3rd,
Affiliations Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, NIAID, National Institutes of Health, Bethesda, Maryland, United States of America, Institute of Infectious Disease and Molecular Medicine, and the Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Rondebosch 7701, South Africa
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Gerhard Walzl,
Affiliation DST/NRF Centre of Excellence for Biomedical TB Research and MRC Centre for TB Research, Division of Molecular Biology & Human Genetics, Department of Biomedical Sciences, Faculty of Medicine & Health Sciences, Stellenbosch University, Cape Town, South Africa
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David Alland
* E-mail: allandda@njms.rutgers.edu
Affiliation Division of Infectious Diseases, Rutgers New Jersey Medical School, ^Rutgers Biomedical & Health Sciences (Formerly UMDNJ), 185 South Orange Avenue, Newark, New Jersey, United States of America
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Bacterial Loads Measured by the Xpert MTB/RIF Assay as Markers of Culture Conversion and Bacteriological Cure in Pulmonary TB
- Shubhada Shenai,
- Katharina Ronacher,
- Stefanus Malherbe,
- Kim Stanley,
- Magdalena Kriel,
- Jill Winter,
- Thomas Peppard,
- Charles E. Barry,
- Jing Wang,
- Lori E. Dodd
- Published: August 10, 2016
- https://doi.org/10.1371/journal.pone.0160062