Endothelial-Specific EphA4 Negatively Regulates Native Pial Collateral Formation and Re-Perfusion following Hindlimb Ischemia

Benjamin Okyere; Kaavya Giridhar; Amanda Hazy; Miao Chen; David Keimig; Robert C. Bielitz; Hehuang Xie; Jia-Qiang He; William R. Huckle; Michelle H. Theus

doi:10.1371/journal.pone.0159930

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Peer-reviewed

Research Article

Endothelial-Specific EphA4 Negatively Regulates Native Pial Collateral Formation and Re-Perfusion following Hindlimb Ischemia

Benjamin Okyere,

Affiliation The Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Insititue and State University, 215 Duck Pond Drive, Blacksburg, Virginia, 24061, United States of America
⨯
Kaavya Giridhar,

Affiliation The Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Insititue and State University, 215 Duck Pond Drive, Blacksburg, Virginia, 24061, United States of America
⨯
Amanda Hazy,

Affiliation The Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Insititue and State University, 215 Duck Pond Drive, Blacksburg, Virginia, 24061, United States of America
⨯
Miao Chen,

Affiliation The Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Insititue and State University, 215 Duck Pond Drive, Blacksburg, Virginia, 24061, United States of America
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David Keimig,

Affiliation Virginia BioComplexity Institute, Virginia Polytechnic Insititue and State University, 1015 Life Science Circle, Blacksburg, Virginia, 24061, United States of America
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Robert C. Bielitz,

Affiliation The Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Insititue and State University, 215 Duck Pond Drive, Blacksburg, Virginia, 24061, United States of America
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Hehuang Xie,

Affiliation Virginia BioComplexity Institute, Virginia Polytechnic Insititue and State University, 1015 Life Science Circle, Blacksburg, Virginia, 24061, United States of America
⨯
Jia-Qiang He,

Affiliation The Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Insititue and State University, 215 Duck Pond Drive, Blacksburg, Virginia, 24061, United States of America
⨯
William R. Huckle,

Affiliation The Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Insititue and State University, 215 Duck Pond Drive, Blacksburg, Virginia, 24061, United States of America
⨯
Michelle H. Theus

* E-mail: mtheus@vt.edu

Affiliation The Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Insititue and State University, 215 Duck Pond Drive, Blacksburg, Virginia, 24061, United States of America
⨯

Endothelial-Specific EphA4 Negatively Regulates Native Pial Collateral Formation and Re-Perfusion following Hindlimb Ischemia

Benjamin Okyere,
Kaavya Giridhar,
Amanda Hazy,
Miao Chen,
David Keimig,
Robert C. Bielitz,
Hehuang Xie,
Jia-Qiang He,
William R. Huckle,
Michelle H. Theus

Published: July 28, 2016
https://doi.org/10.1371/journal.pone.0159930

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