Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms

Gregory V. Schimizzi; Meghan T. Maher; Andrew J. Loza; Gregory D. Longmore

doi:10.1371/journal.pone.0159881

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Research Article

Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms

Gregory V. Schimizzi,

Affiliations ICCE Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Meghan T. Maher,

Affiliations ICCE Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Andrew J. Loza,

Affiliations ICCE Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Computational and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Gregory D. Longmore

* E-mail: glongmore@wustl.edu

Affiliations ICCE Institute, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America
⨯

Disruption of the Cdc42/Par6/aPKC or Dlg/Scrib/Lgl Polarity Complex Promotes Epithelial Proliferation via Overlapping Mechanisms

Gregory V. Schimizzi,
Meghan T. Maher,
Andrew J. Loza,
Gregory D. Longmore

Published: July 25, 2016
https://doi.org/10.1371/journal.pone.0159881

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Cell polarity
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Junctional complexes
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Drosophila melanogaster
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MAPK signaling cascades
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Imaginal discs
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Cell disruption
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Epithelium
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